List of top Animal Biotechnology Questions on Molecular Biology asked in ICAR AIEEA (PG)

Which of the following statements are correct for micro RNA (miRNA)?
(A). Noncoding RNA
(B). Regulates mRNA function
(C). Involve in gene regulation
(D). miRNAs are found in eukaryotes
Choose the correct answer from the options given below:
Newly synthesized tRNA undergoes post transcriptional modifications which include
(A). Nucleotide alkylation
(B). Attachment of \(\text{C}_\text{p}\text{C}_\text{p}\text{A}_\text{OH}\) terminal at 3' end
(C). Attachment of \(\text{C}_\text{p}\text{C}_\text{p}\text{A}_\text{OH}\) terminal at 5' end
(D). Methylation of some bases
Choose the correct answer from the options given below:
The constituent units of a core E.coli DNA polymerase III are
(A). \(\alpha\) (alpha) subunit
(B). \(\epsilon\) (epsilon) subunit
(C). \(\theta\) (theta) subunit
(D). \(\delta\) (delta) subunit
Choose the correct answer from the options given below:
According to Wobble hypothesis GCI present in anticodon arm of tRNA can bind to triplet codons present in mRNA are
(A). 5' CGA 3'
(B). 3' CGA 5'
(C). 5' CGU 3'
(D). 3' CGU 5'
Choose the correct answer from the options given below:
Given below are two statements, one is labelled as Assertion (A) and other one labelled as Reason (R).
Assertion (A): DNA replication is very accurate.
Reason (R): DNA polymerase add correct base with correct hydrogen bonding of the base pair and the common geometry of the standard \(\text{A}=\text{T}\) and \(\text{G}\equiv\text{C}\) base pairs recognized by the active site of polymerase enzyme.
Choose the correct answer from the options given below:
Which of the following statements are correct for a regulatory sequence in a gene?
(A). Provide signal that denote beginning of a gene.
(B). Provide signal that denote end of a gene.
(C). Influence transcription.
(D). Function as initiation point for replication.
Choose the correct answer from the options given below:
The statements true for topoisomerase-I enzyme
(A). Transiently break one of the two DNA strands.
(B). Break both of the strand of double helix DNA.
(C). Change the linking number in increment of one.
(D). Change the linking number by decreasing one.
Choose the correct answer from the options given below:
Watson and Crick base pairing is found in
Covalently modified bases are found in
Which of the following is true for replicative form of single stranded viral DNA
Given below are two statements, one is labelled as Assertion (A) and other one labelled as Reason (R).
Assertion (A): In RNA molecule guanine content is equal to the cytosine content.
Reason (R): Mostly RNAs are single stranded molecule.
In light of the above statements, choose the correct answer from the options given below.
Which of the following statements are true for process of translation?
(A). Either one strand of a double stranded DNA directs the synthesis of mRNA.
(B). Base sequence of transcribed RNA is complimentary to that of DNA strand.
(C). tRNAs molecules align with the mRNA by complimentary base pairing between codons present in the mRNA and anticodon present in the anticodon arm of tRNA.
(D). Amino acids are covalently joined to form a polypeptide chain.
Choose the correct answer from the options given below:
Given below are two statements, one is labelled as Assertion (A) and other one labelled as Reason (R).
Assertion (A): An eukaryotic polypeptide chain containing 100 amino acid residues is coded by a gene containing more than 300 nucleotide bases.
Reason (R): Eukaryotic gene designated for a protein contain both the coding and noncoding part.
In light of the above statements, choose the correct answer from the options given below.
In the sequence 'pApCpGpTpA', the 'p' between 'A' and 'C' represents.
Common covalent modifications in core histone proteins include:
(A) Acetylation
(B) Methylation
(C) Phosphorylation
(D) ADP-ribosylation
Choose the correct answer from the options given below:
Given below are two statements, one is labelled as Assertion (A) and other one labelled as Reason (R).

A : The ends of the chromosomes contain structures called telomeres
R: DNA dependent DNA polymerase is the enzyme responsible for telomere synthesis

In light of the above statements, choose the most appropriate answer from the options given below .
Approximate numbers of proteins present in 40 S subunit of mammalian ribosomes are
40 S subunit of mammalian ribosomes contain
Acetylation of histones H3 and H4 is associated with
Identify the order of post-trancriptional processing of yeast tRNA$^{\text{Tyr}$
(A) Addition of -CCA sequence at 3' end of tRNA
(B) Modification of Uridine to Dihydrouridine
(C) Removal of leader sequence from 5' end of tRNA
(D) Self splicing for removal intervening sequence
Choose the correct answer from the options given below:
Gunaosine, which is a leading nucleotide of the 'CAP' of mRNA is methylated at _____ position.
Which of the following antibiotic specifically inhibits the initiation of transcription in prokaryotes?
(A) Rifampicin
(B) Azithromycin
(C) Rifamycin B
(D) Cordycepin
Choose the correct answer from the options given below:
The inhibition of RNA synthesis in prokaryotes by the action of Actinomycin D emphasis the importance of which of following process?
Match List-I with List-II
List-I (Name of the enzyme in Eukaryotes) vs List-II (Type of RNA synthesized)
(A) RNA Pol I - (I) mRNA
(B) RNA Pol II - (II) tRNA
(C) RNA Pol III - (III) rRNA
Choose the correct answer from the options given below:
In Catabolite repression model of gene regulation, which of the following compound signals the absence of metabolite of choice for the energy to regulate the gene expression?