List of top Questions asked in GPAT- 2021

A compound gives two fragments in a mass spectrometer. They are C19H7N+ and C19H50+. To separate peaks due to these fragments the instrument should have a resolution of
The USP defines as liquid preparations of vegetable drugs, containing alcohol as a solvent or as a preservative, or both, so made that, unless otherwise specified in an individual monograph, each milliliter contains the therapeutic constituents of 1 g of the standard drug that it represents.
One of the following apparatus is used to determine particle size by the gravity sedimentation method
Hemophilia A is caused due to the reduction in the quantity or activity of which of the following clotting factors?
Select the equation that gives the rate of drug dissolution from a tablet
Match List I with List II :

Column I
Name of Meterial 

Column II 
Remark

ABrassesICopper-Tin Alloy
B18/8 Stainless steelIIRigid material
CKeebushIIIChromium and Nickel
DBronzes IVFlexible material
  VCopper-Zinc alloys

Choose the correct answer from the options given below :
A diuretic compound cyclothiazide has a ____ substituent at C-3 of 1,2,4- benzothioadiazine nucleus?
Silver nitrate reagent is used for limit test in Indian Pharmacopoeia for
Prostaglandin analogous have therapeutic utility in the following EXCEPT
Which of the following drug belongs to class of antibiotic called ansamycins?
Vigabatrin produces anti-epileptic activity through
Substitution constant for meta benzoic acids is denoted by
Formation of pyranose structure from glucose leads to formation of diastereoisomers called
When one of the reactants is present in such great excess that its concentration may be considered constant or nearly so, the reaction is said to be of___
Compendium of pharmaceuticals and specialties is an International drug compendia from
Given below are two statements, one is labelled as Assertion (A) and the other is labelled as Reason (R).
Assertion (A): The Ayurvedic drug Asava contains self generated alcohol.
Reason (R): For preparation of Asava the extract of drugs is subjected to a process of calcination.
In light of the above statements, choose the most appropriate answer from the options given below:
Match the following vaccines under Column I with their respective content under Column II.

Column I
Vaccine

Column II 
Content

AOPVIKilled bacteria
BTyphoid (TAB)IILive bacteria 
CTetanusIIIKilled virus
DBCGIVLive virus 
  VToxoid

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HEPA filters are defined as A or more efficient in removing, from the air, B particles generated by vaporization of the hydrocarbon Emory 3004.
Total number of facial bones in the human adult
Conversion of pseudostratified columnar epithelium in chronic bronchitis and bronchiectasis to columnar type epithelium is an example of which type of metaplasia?
Match List I with List II :

Column I
Ingredients Found in Rubber Closures 

Column II 
Example

AActivatorIZinc dibutyldithiocarbamate
BCuring agentIIStearic acid
CAcceleratorIIICarbon black
DFillersIVNeoprene
  VPeroxides

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The split up of time cycle of cardiac cycle
Amine group protection during peptide synthesis can be accomplished by converting the amine to
The absorption maxima of ephedrine hydrochloride and chlorocresol are 257 nm and 279 nm respectively and the A (1%, 1 cm) values in 0.1M hydrochloric acid solution are: 9.0 and zero for ephedrine hydrochloride at 257 nm and at 279 nm respectively. For chlorocresol it is 20.0 and 105.0 at 257 nm and at 279 nm respectively. Calculate the concentration of ephedrine hydrochloride in a batch of Ephedrine hydrochloride injection, diluted 1 to 25 with water, giving the absorbance in 1 cm cell of 0.424 at 279 nm and 0.972 at 257 nm.
The immuno suppressant action of cyclosporine is due to