List of top Pharmaceutical Chemistry Questions on Different classes of therapeutic drugs

5-Fluorouracil, an anti-metabolite used in cancer treatment, is activated to:

Match the following disease with their test for detection:

Disease		Diagnostic tests
P.	Tuberculosis	(i)	Lepromin test
Q.	AIDS	(ii)	ELISA
R.	Syphilis	(iii)	Mantoux test
S.	Leprosy	(iv)	Kahn's test

Which of the following drug does NOT require therapeutic drug monitoring:

Tetracycline undergoes epimerization at C4 between pH 4-8 to give:

Which ring of warfarin is essential for its therapeutic activity:

The fluoroquinolones act by:

Match the following antibodies with their correct description:

Antibody	Description
P. IgE	(i) Cross the placenta
Q. IgG	(ii) Dominant antibody produced in immune responses
R. IgM	(iii) It is found in the mother's milk
S. IgA	(iv) Responsible for autoimmune responses including allergies

Which among the following is not used as NSAID?

Which metabolite is used to inactivate the vasico-toxic metabolite leading to hemorrhagic cystitis by alkylating agent used in the treatment of cancer

Which of the following is a 4th Generation Cephalosporin?

Select the correct set of anticancer drugs that belong to “pyrimidine and related compounds”:

Which of the following is a third generation cephalos-Porin?

What do you mean by Orphan Drug?

Which of the following drug used in the chemotherapy of some types of leukemia, satisfies the statements:
Statement I: It is effective orally.
Statement II: It has near 100% oral bioavailability. 
In light of the above statements, choose the correct answer from the options given below:

Which of the following is NOT an example of an mTOR inhibitor?

Reason for the combination of Diphenoxylate (2.5 mg) + Atropine (0.025 mg) is to

Which of the following statement/s are correct regarding the alkylating agents as anticancer agents:
A. They get converted into highly nucleophilic anions and bind to the nitrogen atom of guanine intercalating the DNA strands
B. Cyclophosphamide and busulfan belong to this class 
C. They inhibit the DNA synthesis by inhibiting the DNA polymerase enzyme 
D. They inhibit the DNA supercoiling by irreversibly inhibiting the DNA topoisomerase enzyme 
Choose the correct answer from the options given below:

A diuretic compound cyclothiazide has a ____ substituent at C-3 of 1,2,4- benzothioadiazine nucleus?

Vigabatrin produces anti-epileptic activity through

Prostaglandin analogous have therapeutic utility in the following EXCEPT