List of top Pharmaceutical Chemistry Questions

Match the following disease with their test for detection:

Disease		Diagnostic tests
P.	Tuberculosis	(i)	Lepromin test
Q.	AIDS	(ii)	ELISA
R.	Syphilis	(iii)	Mantoux test
S.	Leprosy	(iv)	Kahn's test

In a homologous series of any general anesthetic, increasing the chain length increases the lipid solubility, and produce a corresponding increase in anesthetic potency, is proposed by:

The fluoroquinolones act by:

5-Fluorouracil, an anti-metabolite used in cancer treatment, is activated to:

Which ring of warfarin is essential for its therapeutic activity:

Examples of BCS class III drugs are:

Tetracycline undergoes epimerization at C4 between pH 4-8 to give:

Which of the following drug does NOT require therapeutic drug monitoring:

Which of the following is a third generation cephalos-Porin?

Which among the following is not used as NSAID?

Match List I with List II:

List I Name of the drug		List II Chemical class
A.	Zolpidem	I.	Cyclopyrrolone
B.	Zaleplon	II.	Benzodiazepine
C.	Zopiclone	III.	Imidazopyridine
D.	Triazolam	IV.	Pyrazolopyrimidine

Choose the correct answer from the options given below

Which of the following compound would be expected to have greatest florescence?

Which of the following drug used in the chemotherapy of some types of leukemia, satisfies the statements:
Statement I: It is effective orally.
Statement II: It has near 100% oral bioavailability. 
In light of the above statements, choose the correct answer from the options given below:

Which of the following is NOT an example of an mTOR inhibitor?

What do you mean by Orphan Drug?

Select the correct set of anticancer drugs that belong to “pyrimidine and related compounds”:

Which of the following is a 4th Generation Cephalosporin?

Which metabolite is used to inactivate the vasico-toxic metabolite leading to hemorrhagic cystitis by alkylating agent used in the treatment of cancer

Identify the functional groups from the below mentioned options that lead to weakening of benzoic acid:
(A):–OH
(B):–Cl
(C):–NH₂
(D):–NO₂

Citric acid cycle is the final pathway during the oxidation of _______ .

Heme is ____ .

All enzymes accelerate the reaction rates by______________ .

A patient with pheochromocytoma is undergoing surgery and has not been administered with alpha receptor blocker. If he is administered with intravenous propranolol, then which of the following effects will be evident?

Reason for the combination of Diphenoxylate (2.5 mg) + Atropine (0.025 mg) is to

Which of the following statement/s are correct regarding the alkylating agents as anticancer agents:
A. They get converted into highly nucleophilic anions and bind to the nitrogen atom of guanine intercalating the DNA strands
B. Cyclophosphamide and busulfan belong to this class 
C. They inhibit the DNA synthesis by inhibiting the DNA polymerase enzyme 
D. They inhibit the DNA supercoiling by irreversibly inhibiting the DNA topoisomerase enzyme 
Choose the correct answer from the options given below: