Question

Which of the following statement/s are correct regarding the alkylating agents as anticancer agents:
A. They get converted into highly nucleophilic anions and bind to the nitrogen atom of guanine intercalating the DNA strands
B. Cyclophosphamide and busulfan belong to this class 
C. They inhibit the DNA synthesis by inhibiting the DNA polymerase enzyme 
D. They inhibit the DNA supercoiling by irreversibly inhibiting the DNA topoisomerase enzyme 
Choose the correct answer from the options given below:

• A. A, B and D only are correct
• B. Only B is correct
• C. Only A and B are correct
• D. All A, B, C and D are correct

Answer 1

The Correct Option is B

The correct option is (B): Only B is correct