Question

The fluoroquinolones act by:

• A. Inhibiting folic acid synthesis, reducing nucleotide production and DNA synthesis
• B. Inhibiting DNA gyrase and topoisomerase IV, causing supercoiling and fragmentation of bacterial DNA
• C. Disrupting peptidoglycan cross-linking, weakening the bacterial cell wall
• D. Inhibiting ribosomal subunits, leading to the cessation of protein synthesis

Answer 1

The Correct Option is B

The correct option is (B): Inhibiting DNA gyrase and topoisomerase IV, causing supercoiling and fragmentation of bacterial DNA.