For a double strand DNA, one strand is given below:
The amount of energy required to split the double strand DNA into two single strands is _____ kcal mol
−1.
[Given: Average energy per H-bond for A-T base pair = 1.0 kcal mol
−1, G-C base pair = 1.5 kcal mol
−1, and A-U base pair = 1.25 kcal mol
−1. Ignore electrostatic repulsion between the phosphate groups.]