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IIT Guwahati researchers develop four organic co-crystals with broad applications in drug discovery, imaging, communication, and optical devices, marking a significant stride in semiconductor technology, published in Nature Communications.
New Delhi: Researchers at IIT Guwahati have made significant progress in co-crystal engineering, a technique aimed at merging compounds to amplify their functionality. The findings of this research open doors for innovative applications and technologies, signifying several milestones in co-crystal engineering.
The IIT Guwahati researchers have crafted four innovative organic photo-functional co-crystals Led by Prof Parameswar K Iyer of IIT Guwahati in collaboration with scientists from the University of Hyderabad and IISc Bengaluru.
About IIT Guwahati’s Research on Organic Co-Crystal Systems for Advanced Applications
Co-crystals hold immense promise across various fields such as drug development, materials science, semiconductor devices, and sustainable chemistry. However, the challenge arises from the typical planar and rigid nature of most co-crystals, leading to clumping and reduced efficiency, known as aggregation-caused quenching (ACQ), limiting their potential applications.
These co-crystals exhibit a remarkable ability to emit light efficiently with minimal loss, marking a significant breakthrough in the field.
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Prof Parameswar K Iyer, from the Department of Chemistry & Centre for Nanotechnology at IIT Guwahati, shared, "In our research, we engineered four luminescent Co-Crystals using a compound called Twisted Aromatic Hydrocarbons (TAH). The TAH is distorted in nature, leading to intriguing electronic and optical properties. By adjusting the molecular structures, we formed a novel yet unusually highly efficient cis-isomeric co-crystal."
The novel co-crystals, namely TAHOFN, TAHTFPN_G, TAHTFPN_O, and TAHTCNB, exhibit unique properties such as Delayed Fluorescence, Room Temperature Phosphorescence, and Aggregation-induced emission enhancement (AIEE).
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These properties make them shine brightly when clustered together, aiding clearer signals. This brightness and clarity have proved to be valuable for studying cells, particularly in biomedical applications.
These organic co-crystals hold significant promise beyond their potential in cancer therapy. They possess efficient light-guiding properties, showcasing the potential for advanced technologies, especially in high-speed internet communication through fiber-optic cables.
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