Question

Which one or more of the following statements correctly describe(s) the addition of N-nucleotides during the rearrangement of the immunoglobulin heavy chain- encoding gene?

• A. Addition of N-nucleotides is template encoded
• B. N-nucleotides are added by terminal deoxynucleotidyl transferase
• C. The added N-nucleotides are common in V-D and D-J junction
• D. N-nucleotides are added by the DNA polymerase II.

Answer 1

The Correct Option is B, C

The correct options are: (B): N-nucleotides are added by terminal deoxynucleotidyl transferase(C):The added N-nucleotides are common in V-D and D-J junction.