Step 1: Understanding the Concept:
Globular proteins have specific structural features.
They are different from fibrous proteins.
Step 2: Key Formula or Approach:
No specific formula.
Need to understand the properties of globular proteins.
Step 3: Detailed Explanation:
A. Polypeptide chains are folded into a spherical shape - correct.
B. Globular proteins often contain multiple types of secondary structure - incorrect.
C. Most naturally occurring enzymes are globular proteins - correct.
D. Most regulatory proteins are globular proteins - correct.
Thus, A, C, and D are correct.
Step 4: Final Answer:
The correct statements are A, C, and D.
Hence, the correct option is (B).