Which of the following statements are correct for the denaturation of protein?
A. Many proteins are denatured with change in pH
B. Many proteins are denatured with change in temperature
C. Many proteins are denatured by contact with the glass and plastic surface
D. Denaturation is a completely irreversible process
Choose the correct answer from the options given below:
Show Hint
Denaturation: loss of native structure.
Causes: pH, temperature, detergents, surfaces.
Some proteins can renature (reversible denaturation).
Step 1: Understanding the Concept:
Denaturation is the loss of protein structure.
It can be caused by various factors. Step 2: Key Formula or Approach:
No specific formula.
Need to understand protein denaturation. Step 3: Detailed Explanation:
A. pH changes can denature proteins - correct.
B. Temperature changes can denature proteins - correct.
C. Contact with glass and plastic surfaces can denature proteins - correct.
D. Denaturation is not always irreversible.
Some proteins can renature (e.g., ribonuclease) - incorrect.
Thus, A, B, and C are correct. Step 4: Final Answer:
The correct statements are A, B, and C.
Hence, the correct option is (B).
