Question:

Which of the following statement about the tails of the histone molecules is NOT true?

Show Hint

Histone tails: N-terminal, unstructured, modified.
Not required for nucleosome association.
Important for chromatin regulation.
  • N-terminal extension
  • Lack defined structure
  • Site for extensive modifications
  • Required for the association of nucleosome
Show Solution
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The Correct Option is D

Solution and Explanation

Step 1: Understanding the Concept:
Histone tails are important for chromatin structure.
They have specific features.

Step 2: Key Formula or Approach:

No specific formula.
Need to understand histone tail properties.

Step 3: Detailed Explanation:

Histone tails:
- Are N-terminal extensions (A is true).
- Lack defined structure (B is true).
- Are sites for extensive modifications (C is true).
Histone tails are NOT required for the association of nucleosomes.
The core histones are required for nucleosome association.
Thus, D is not true.

Step 4: Final Answer:

The statement "Required for the association of nucleosome" is NOT true.
Hence, the correct option is (D).
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