Question:
Which of the following enzymes require thiamine pyrophosphate as a coenzyme for their activity?
A. Pyruvate decarboxylase
B. Pyruvate dehydrogenase
C. Transketolase
D. Malate dehydrogenase
Choose the correct answer from the options given below:
Which of the following enzymes require thiamine pyrophosphate as a coenzyme for their activity?
A. Pyruvate decarboxylase
B. Pyruvate dehydrogenase
C. Transketolase
D. Malate dehydrogenase
Choose the correct answer from the options given below:
A. Pyruvate decarboxylase
B. Pyruvate dehydrogenase
C. Transketolase
D. Malate dehydrogenase
Choose the correct answer from the options given below:
Show Hint
TPP-dependent enzymes:
Pyruvate dehydrogenase, Pyruvate decarboxylase, Transketolase.
TPP is derived from vitamin B1 (thiamine).
Pyruvate dehydrogenase, Pyruvate decarboxylase, Transketolase.
TPP is derived from vitamin B1 (thiamine).
Updated On: Aug 18, 2026
- A, B and D only
- A, B and C only
- A, C and D only
- B, C and D only
Show Solution
Verified By Collegedunia
The Correct Option is B
Solution and Explanation
Step 1: Understanding the Concept:
Thiamine pyrophosphate (TPP) is a coenzyme.
It is required by several enzymes.
Step 2: Key Formula or Approach:
No specific formula.
Need to know which enzymes require TPP.
Step 3: Detailed Explanation:
A. Pyruvate decarboxylase requires TPP - correct.
B. Pyruvate dehydrogenase requires TPP - correct.
C. Transketolase requires TPP - correct.
D. Malate dehydrogenase does not require TPP - incorrect.
Thus, A, B, and C are correct.
Step 4: Final Answer:
The enzymes that require TPP are A, B, and C.
Hence, the correct option is (B).
Thiamine pyrophosphate (TPP) is a coenzyme.
It is required by several enzymes.
Step 2: Key Formula or Approach:
No specific formula.
Need to know which enzymes require TPP.
Step 3: Detailed Explanation:
A. Pyruvate decarboxylase requires TPP - correct.
B. Pyruvate dehydrogenase requires TPP - correct.
C. Transketolase requires TPP - correct.
D. Malate dehydrogenase does not require TPP - incorrect.
Thus, A, B, and C are correct.
Step 4: Final Answer:
The enzymes that require TPP are A, B, and C.
Hence, the correct option is (B).
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