Question

Which of the following are correct for proline?
A. It is also called imino acid
B. Its "R"-Group (Side chain) is a hydrogen atom
C. Incorporation of proline in helical structure disrupts the \(\alpha\)-helical structure
D. It contains a free \(\alpha\)-carboxylic acid group and a free \(\alpha\)-amino group
Choose the correct answer from the options given below:

• A. A, B and D only
• B. A, B and C only
• C. A and C only
• D. A and D only

Hint:

Proline: imino acid, disrupts \(\alpha\)-helices.
R-group: cyclic structure (pyrrolidine ring).
Found in turns and loops.

Answer 1

The Correct Option is C

Step 1: Understanding the Concept:
Proline is a special amino acid.
It has unique structural features.

Step 2: Key Formula or Approach:
No specific formula.
Need to know the properties of proline.

Step 3: Detailed Explanation:
A. Proline is an imino acid (actually, it is an amino acid with a ring structure) - correct.
B. Proline's R-group is not hydrogen (glycine has hydrogen) - incorrect.
C. Proline disrupts \(\alpha\)-helical structure - correct.
D. Proline has a free \(\alpha\)-carboxylic acid and \(\alpha\)-amino group - correct.
But the R-group is not hydrogen.
Thus, A and C are correct.

Step 4: Final Answer:
The correct statements are A and C.
Hence, the correct option is (C).