Step 1: Understanding the Concept:
Antibiotic residues can enter the milk supply if dairy animals are treated for infections (like mastitis) and milked before the mandatory drug withdrawal period has elapsed.
Step 2: Detailed Explanation:
- When milk containing antibiotic residues is used to manufacture fermented dairy products (like cheese, yogurt, dahi, or shrikhand), the antibiotics inhibit the growth and metabolic activity of the lactic acid starter cultures.
- This inhibition prevents acid production, pH reduction, and curd formation, a serious processing defect known as starter failure.
- Aside from starter failure, antibiotic residues also present significant public health risks, including the development of antibiotic-resistant bacteria and allergic reactions in sensitive consumers.
Step 3: Final Answer
The major technological significance of antibiotic residues in milk is starter failure.