Question

Tertiary alkyl halides are least reactive towards SN2 reaction.

Hint:

Steric hindrance in tertiary alkyl halides prevents effective nucleophilic attack, making them less reactive in SN2 reactions.

Answer 1

Tertiary alkyl halides are least reactive towards the SN2 reaction because the bulky alkyl groups around the carbon atom hinder the attack of the nucleophile. The crowded environment prevents the nucleophile from approaching the carbon center effectively, slowing the reaction.