Question:

Parkinson's disease is linked to abnormalities in the levels of dopamine in the body. The structure of dopamine is

Updated On: Jun 3, 2024
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Dopamine is produced in several areas of the brain. If the amount of dopamine increases in the brain, the patient may be affected with Parkinson's disease. The IUPAC name of dopamine is 2-(3,4-dihydroxyphenyl) ethylamine and its structure is as follows :
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Ans. Parkinson's disease is a degenerative condition brought on by nerve cell degeneration in the region of the brain known as the substantia nigra, which regulates movement. 

  • These nerve cells pass away or suffer damage, reducing the capacity to make the crucial neurotransmitter dopamine
  • According to studies, Parkinson's symptoms appear in people whose substantia nigra dopamine-producing cells have been lost by 80% or more. 
  • Parkinson's disease is a neurological illness that impairs movement, balance, and coordination as well as produces tremors and stiffness. 
  • Parkinson's disease symptoms often start out mildly and get worse with time. 
  • As the illness worsens, patients could find it difficult to move and communicate. 
  • In addition, people could have behavioral and mental changes, sleep problems, depression, memory problems, and tiredness. 
  • The chemical messenger that carries signals between the corpus striatum and the substantia nigra is dopamine. 
  • This is sometimes referred to as the nigrostriatal route in research. 
  • The basal ganglia include the substantia nigra and corpus striatum.
  • Movement issues may come from aberrant nerve firing patterns brought on by low amounts of dopamine that impair the nigrostriatal pathway. 
  • By the time they experience symptoms, most patients with Parkinson's disease (PD) have lost 60 to 80%Trusted Source or more of their substantia nigra's dopamine-producing cells.
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Chemistry in Everyday Life

The scientific study of matter’s properties and behaviour is known as chemistry. It is a natural science that studies the elements that makeup matter, as well as the compounds, made up of atoms, molecules, and ions: their composition, structure, qualities, and behaviour, as well as the changes that occur when they mix with other things.

  • Importance of Chemistry in Food - Chemicals are the fundamental components of everything. Chemical molecules make up all food, including carbs, vitamins, lipids, proteins, and fibre, which are all safe and often desirable.
  • Importance of Chemistry in Medicines - Medicines or pharmaceuticals are chemical substances that are used to treat diseases and relieve pain. Chemistry has made significant contributions to health care. Chemistry, for example, aids in the manufacture and application of surgical materials.
  • Importance of Chemistry in Cosmetics - In our daily lives, we use lotions, fragrances, talcum powder, and a variety of other cosmetic goods. All of these items are developed in laboratories using chemicals for our health and skin.
  • Importance of Chemistry in Soaps and Detergents - Soaps are sodium and potassium salts of fatty acids with greater molecular weights, such as stearic acid, palmitic acid, and oleic acid. Sodium salts of long-chain alkyl hydrogen sulphates or sodium salts of long-chain alkyl benzene sulphonic acids are commonly used as detergents.