Question:
Which one of the following small RNAs in plants DO NOT regulate gene expression by cleavage of mRNAs?
Which one of the following small RNAs in plants DO NOT regulate gene expression by cleavage of mRNAs?
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Heterochromatin = Closed/DNA level; so hcsiRNAs work on DNA, not mRNA.
Updated On: May 14, 2026
- MicroRNAs (miRNAs)
- Short interfering RNA (siRNA)
- Heterochromatin siRNAs (hcsiRNAs)
- Trans-acting siRNAs (tasiRNAs)
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The Correct Option is C
Solution and Explanation
Step 1: Concept
Small RNAs regulate genes through Post-Transcriptional Gene Silencing (PTGS) or Transcriptional Gene Silencing (TGS).
Step 2: Meaning
PTGS involves the direct degradation (cleavage) or translational inhibition of mRNA in the cytoplasm.
Step 3: Analysis
miRNAs, siRNAs, and tasiRNAs primarily target mRNA for cleavage. hcsiRNAs, however, are involved in the RNA-directed DNA methylation (RdDM) pathway, which functions in the nucleus to modify chromatin and silence transcription at the DNA level.
Step 4: Conclusion
hcsiRNAs regulate gene expression through epigenetic modifications of DNA/chromatin rather than mRNA cleavage. Final Answer: (C)
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