Question:

Which one of the following nucleosides has been shown to be functioning as a local hormone to control various physiological functions in humans?

Show Hint

Adenosine:
- Local hormone and neuromodulator.
- Regulates blood flow, heart rate, sleep, and inflammation.
- Caffeine acts as an adenosine receptor antagonist.
  • Adenosine
  • Inosine
  • Guanosine
  • Cytidine
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The Correct Option is A

Solution and Explanation

Step 1: Understanding the Question:
This question tests knowledge of nucleosides and their physiological roles.

Step 2: Detailed Explanation:

Adenosine functions as a local hormone and neuromodulator.
It regulates many physiological functions:
- Vasodilation
- Heart rate
- Sleep regulation
- Inflammation
- Neurotransmission
Adenosine receptors are widespread in the body.
Inosine (B) is a breakdown product of adenosine.
Guanosine (C) and Cytidine (D) are not known as local hormones.
Thus, adenosine is the correct answer.

Step 3: Final Answer:

Thus, adenosine functions as a local hormone, which corresponds to option (A).
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