Question

The technology used for production of monoclonal antibodies is called

• A. Glaucoma
• B. Melanoma
• C. Hybridoma
• D. Myeloma

Hint:

Hybridoma = B-lymphocyte (produces antibodies) + Myeloma cell (immortal cancer cell).
It is an essential biotechnological tool used for diagnosing aquatic pathogens and developing targeted therapeutics.

Answer 1

The Correct Option is C

Step 1: Understanding the Concept:
Monoclonal antibodies are highly specific antibodies produced from a single clone of cells, allowing them to bind selectively to a single epitope of an antigen.

Step 2: Detailed Explanation:
Hybridoma technology (developed by Georges Köhler and César Milstein in 1975) is used for producing monoclonal antibodies.
This technique involves fusing short-lived, antibody-producing B-lymphocytes (from immunized animals) with immortal, fast-growing cancerous myeloma cells.
The resulting fused hybrid cells, called hybridomas, possess the combined properties of producing highly specific antibodies (from B-cells) and multiplying indefinitely in culture (from myeloma cells).

Step 3: Final Answer:
The technology is called Hybridoma, which corresponds to option (C).