Concept:
Blood is composed of cellular elements and plasma proteins, each having specific roles in oxygen transport, immunity, and antigen-antibody reactions.
Step 1: Understanding Red Blood Cells (A).
Red blood cells (RBCs) contain hemoglobin and are responsible for transporting oxygen to body tissues.
Thus, A $\rightarrow$ IV.
Step 2: Understanding Leukocytes (B).
Leukocytes or white blood cells are responsible for defending the body against infections and foreign invaders.
Thus, B $\rightarrow$ III.
Step 3: Understanding Antigens (C).
Antigens are substances present on the surface of red blood cells that determine blood groups (e.g., ABO system).
Thus, C $\rightarrow$ II.
Step 4: Understanding Antibodies (D).
Antibodies are proteins present in plasma that react specifically with antigens to neutralize them.
Thus, D $\rightarrow$ I.
Step 5: Forming correct combination.
\[
A-IV,\quad B-III,\quad C-II,\quad D-I
\]
Final Conclusion:
Hence, the correct answer is option (1).