For DNA replication, which of the following statements are true?
A. Circular chromosome of E.coli replicates through multiple origin of replication.
B. In each linear chromosome of eukaryote, DNA replication begins when replication bubbles form at multiple sites along giant DNA molecule.
C. In each linear chromosome of eukaryote, DNA replication begins when replication bubbles form at single site along giant DNA molecule.
D. In circular chromosome of E.coli, one origin of replication is present.
Choose the correct answer from the options given below