Question:
Choose the correct combination of excipients and their toxicity:
Choose the correct combination of excipients and their toxicity:
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Talc = Lung issues; Limonene = Hyaline droplets. These are classic toxicology pairings.
Updated On: May 28, 2026
- A & B Only
- A & C Only
- B & C Only
- A, C & D Only
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The Correct Option is A
Solution and Explanation
Step 1: Concept
While excipients are generally inert, some can exhibit specific toxicities or adverse effects in high doses or specific models.
Step 2: Meaning
A. Talc is linked to lung tumors in female rats. B. Limonene is associated with hyaline droplet formation in male rat kidneys. C. Tartrazine is known for hypersensitivity/allergy. D. Menthol can cause localized irritation/dermatitis.
Step 3: Analysis
Statements A and B accurately reflect established toxicological data for those specific excipients in animal models. C is incorrectly labeled as cardiac toxicity , and D (while possible) is less definitive in this technical context.
Step 4: Conclusion
Only combinations A and B are correct.
Final Answer: (A)
While excipients are generally inert, some can exhibit specific toxicities or adverse effects in high doses or specific models.
Step 2: Meaning
A. Talc is linked to lung tumors in female rats. B. Limonene is associated with hyaline droplet formation in male rat kidneys. C. Tartrazine is known for hypersensitivity/allergy. D. Menthol can cause localized irritation/dermatitis.
Step 3: Analysis
Statements A and B accurately reflect established toxicological data for those specific excipients in animal models. C is incorrectly labeled as cardiac toxicity , and D (while possible) is less definitive in this technical context.
Step 4: Conclusion
Only combinations A and B are correct.
Final Answer: (A)
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