List of top Questions asked in NMAT by GMAC

Scientists seeking view new ways to repair damaged arteries and ailing hearts have coaxed stem cells from a human embryo into forming tiny blood vessels. It’s the first time human embryonic stem cells have been nurtured to the point where they will organize into blood vessels that could nourish the body, according to Robert Langer, leader of a laboratory team at the Massachusetts Institute of Technology. But it isn’t likely to be the last, as scientists pursue research into uses for stem cells despite debate over the ethics of using the cells. The new development was reported in Tuesday’s online issue of proceedings of the National Academy of Sciences. Dr. John Gearhart of the Johns Hopkins Schools of Medicine said research was a “nice illustration” of how stem cells can serve as a source of various types of cells, in this case for blood vessels. “I think this is terrific” said Gearhart, who was not part of the research team. “It’s another good example of the isolation of an important cell type from human embryonic stem cells.” “These are the kinds of papers we are going to see a lot of,” Gearhart added. Langer said the work showed that endothelial cells could be made from human embryonic stem cells. Endothelial cells have veins, arteries and lymph tissue. They are key to the structures that carry blood throughout the body. He said that if the technique we refined, scientists would eventually be able to make in the laboratory blood vessels that could be used to replace diseased arteries in the body: “There are thousands of operations a year now where doctors take vessels from one part of the body and transplant them to another,” said Langer. Eventually, he said, such vessels might be made outside the body from embryonic stem cells. Langer said endothelial cells also might be used to restore circulation to cells damaged by heart attacks. He said the processed stem cells may be able to reestablish blood flow to hearts failing due to blocked arteries. The research was conducted under a private grant, but Langer said the cell culture used is one of 61 worldwide that have been approved by the National Institutes of Health for federally funded research. The use of embryonic stem cells is controversial because extracting the cells kills a living human embryo. President Bush last summer decided that federal funding would be permitted only for stem cell cultures that already existed and were made from embryos that were to be discarded by fertility clinics. The aim was to prevent further killing for research purposes of other human embryos. Langer said his lab will seek federal money to continue research using the same stem cell cultures, which were obtained from the Ram Bam Medial Center in Haifa, Israel. Embryonic stem cells are the ancestral cells of every cell in the body. In a developing embryo, they transform into cells that make up the organs, bone, skin and other tissues. Researchers hope to direct the transformation of such cells to treat ailing hearts, livers, brains and other organs. Langer said his team cultured the cells in such a way that they were allowed to develop into the various types of cells that are precursors to mature tissue. From this colony, the researchers extracted cells that were following a linage that would lead to mature endothelial cells. These were further cultured and some eventually formed primitive vascular structures.
I suppose the vitality of a group, an individual or a society is measured by the extent to which it posses courage and above all, creative imagination. If that imagination is lacking our growth becomes more and more stunted, which is a sign of decay. What then is happening. Today? Are we trying to improve in this respect or are we merely functioning somewhere on the surface without touching the reality which is afflicting on the surface without touching the reality which is afflicting the world & which may result in political conflict, economic warfare or world war? So, when there are discussions on the concept of man as visualized in the Eastern Ideal or The Western Ideal. They interest me greatly from a historical point of view and from a cultural point of view, although I have always resisted this idea of dividing the world into the orient and occident, I do not believe in such divisions. There have, of course, been differences in racial and nation of outlook and in ideals but to talk of the east & west as such as little meaning. I can see the difference between an industrialized and a non-industrialised country. I think the difference, say, between India and Europe in the middle ages, would not have been very great and would have been comparable to the difference between any of the great countries of Asia today. I feel that we think roughly because we are misled in our approach. Differences have crept in and been intensified by this process of industrialization & mechanization which has promoted material well being tremendously and which has been a blessing to humanity. At the same time, it is corroding the life of the mind & thereby encouraging a process of self destruction. I am not for the moment talking or thinking about wars and the like we have seen in history races come up and gradually fade away in Asia, in Europe and other places. Are we witnessing the same thing today? It may be that this will not take effect in our lifetime. In the past anyway, one great consolation was that things happened only in one particular greater of the world. If there was a collapse in one part of the world, the other part carried on. No part will be left to survive, as it could in older times. During the so called Dark ages of Europe, there were bright periods in Asia, in China, in India, in the middle east and else where. In the old days if progress was limited, disaster was also limited in extent and intensity. Today, when we have arrived at a period of great disaster and it is a little difficult for us to choose a middle way which would unable us to achieve a little progress and, at the same time to limit the scope of disaster. That is the major question. A person who has to carry a burden of responsibility is greater troubled by the practical aspects of this question. Am I right in saying that the mental life of the world is in a process of deterioration, chiefly because the environment that has been created by the Industrial Revolution does not give time or opportunity to individuals to think? I do not deny that today there are many great thinkers but it is quite likely that they might be submerged in the mass of unthinking humanity. We are dealing with and talking a great deal about democracy and I have little doubt that democracy is the best of all the various methods available to us for the governance of human beings. At the same time, we are using today-by today I mean the last two decades or sothe emergence of democracy in a somewhat uncontrolled form. When we think of democracy, we normally think of it in the rather limited sense of the 19th century or the early 20th century use of the term. Owing to the remarkable technological growth, something has happened since then and meanwhile democracy has also spread. The result is that we have vast masses of human beings brought up by the Industrial Revolution, who are not encouraged or given an opportunity to think much. They live a life which, from the point of view of physical comfort, is incomparably better than it has been in any previous generation, but they seldom have a chance to think. And yet in a democratic system, it is this vast mass of human beings that will ultimately govern or elect those who govern.