List of top Biochemistry Questions asked in Graduate Pharmacy Aptitude Test

Which of the reagent from the given can be used to protect ketone group

Match the following enzymes/protein with specific functions in DNA replication

(1)	Helicases	(P)	Processive unwinding of DNA
(2)	DNA Primses	(Q)	Seals the single strand
(3)	DNA ligases	(R)	Relieves torsional strain
(4)	Topiosomerases	(S)	Initates synthesis of RNA Primers

Thiamine deficiency causes decreased energy production because

Which of the following is most likely to undergo lysis

Tamoxifen is nonsteroidal drug acting at steroid receptor(s) It produces which type of effects

(P) Androgen

(Q) Antiestrogen

(R) Antiprogestogen

(S) Estrogen

In mammals, The major fat in adipose tissue is:

Proton pump inhibitors are most effective when given

Match compounds is Group I with inhibitory activities in Group II

Group I		Group II
(P)	Vancomycin	(1)	Folate metabolism
(Q)	Rifampin	(2)	DNA synthesis
(R)	Puromycin	(3)	Protein synthesis
(S)	Ciprofloxacin	(4)	RNA synthesis
		(5)	Cell wall systhesis

Formation of Okazaki occurs in

All of the following is resistant to both true and pseudo cholinesterase enzymes

What is the relationship between keto and enol tautomers

Increase in melting temperature of DNA is due to high content of

Ferritin is:

Cholesterol contributors to___Of the biological membrane

Match the following biochemical transformations with coenzymes involved

(i) α-Ketoglutarate to glutamic acid	Tetrahydrofalate
(ii) Uridine to thymidine.	NADH
(iii) Pyruvid acid to acetyl coenzyme A	Thiamine pyrophosphate
	Pyridoxamine

The reaction of the citric acid cycle that is most similar to the pyruvate dehydrogenase complex catalyzed conversion of pyruvate to acetyl-CoA is the conversion of

A set of closely related genes of generic markers that are inherited as a single unit is

Deoxy position of deoxyribose in DNA is at.............

All are potent 3A4 inhibitors EXCEPT____

The enzyme superoxide dismutase (SOD) converts

Which one of the following amino acid residues is specifically recognized by chymotrypsin during peptide bond cleavage

Vitamin K is constituted of_______ring.

An alternaive to glycolysis pathway is______

Which of the following is produced in phenyl propanoid pathway

Living cells are negatively charged inside primarily because____