List of top Biotechnology Questions on Genetics

A cDNA was synthesized from the mRNA of a eukaryotic gene. After cloning and sequence analysis, the double-stranded cDNA of 614 bp revealed 125 bp 5'-UTR and 120 bp 3'-UTR. The number of amino acids present in the polypeptide encoded by this gene is ............... (answer in integer)

A rare genetic disorder resulting from homozygosity for a recessive allele (\( r \)) occurs in 2 out of every 10,000 individuals in a population. Assuming that (i) the disorder is not lethal, (ii) the disorder does not impact reproductive success, (iii) no new mutations are introduced in the population, and (iv) the population follows Hardy-Weinberg equilibrium, the percentage (%) of the carriers in the population that pass the \( r \) allele to offspring is .......... (rounded off to 1 decimal)

In a plant species, the genotype \( DDEE \) is crossed with the genotype \( ddee \); and the F1 is test crossed. Considering that the two genes are linked and 20 map unit (cM) apart in the chromosome, the percentage (%) of the test cross progeny with the genotype \( ddee \) is ........................ (answer in integer)

In a farm animal breeding programme, the animal with the dominant A phenotype, the recessive b phenotype, the dominant D phenotype, and the recessive e phenotype are commercially important. The inheritance of these traits follows Mendelian laws. From the tetra-hybrid cross of two genotypes AaBbDdEe and AaBbDdEe, the expected frequency of offspring that will show all the above-mentioned desired phenotypes is ................... (rounded off to 3 decimals)

Which of the following statement(s) is/are CORRECT for lac repressor expressed from the lacI gene?

Which of the following statement(s) is/are CORRECT in the classical ‘ABC model’ for genetic control of flower development?

The method(s) used to detect a DNA fragment of 150 base pairs is/are

The first evidence of ‘gene transfer’ was demonstrated in 1928 by

In humans, Down syndrome is caused by

DNA sample collected from an unidentified bacterial species (Y) contains \(13%\) adenine. The \(G{+}C\) content (in percentage) of Y is ________________.

Methylation of CpG islands near the promoter of a gene can inhibit transcription by

Fabry disease in humans is a X-linked disease. The probability (in percentage) for a phenotypically normal father and a carrier mother to have a son with Fabry disease is ________________.