Question:
Which one of the following vaccines is commonly produced by using class B SPF eggs?
Which one of the following vaccines is commonly produced by using class B SPF eggs?
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Marek's disease vaccines require live cell-associated preparations, making SPF eggs and primary embryo fibroblast cultures essential for their manufacturing.
Updated On: Jul 8, 2026
- Infectious bronchitis
- Infectious bursal disease
- Marek's disease
- Avian influenza
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The Correct Option is C
Solution and Explanation
Step 1: Understanding the Concept:
Specific Pathogen Free (SPF) embryonated chicken eggs are critical for producing high-quality poultry vaccines to prevent contamination with extraneous pathogens.
Step 3: Detailed Explanation:
1. Marek's disease is a highly contagious lymphoproliferative disease of poultry caused by a herpesvirus.
2. The vaccine for Marek's disease is cell-associated and is produced using primary cell cultures—specifically, Chicken Embryo Fibroblasts (CEF)—derived from embryonated SPF eggs.
3. Class B SPF eggs are highly utilized for this purpose to ensure the resulting cell culture remains free of any vertically transmissible avian pathogens.
Step 4: Final Answer
The correct option is (C).
Specific Pathogen Free (SPF) embryonated chicken eggs are critical for producing high-quality poultry vaccines to prevent contamination with extraneous pathogens.
Step 3: Detailed Explanation:
1. Marek's disease is a highly contagious lymphoproliferative disease of poultry caused by a herpesvirus.
2. The vaccine for Marek's disease is cell-associated and is produced using primary cell cultures—specifically, Chicken Embryo Fibroblasts (CEF)—derived from embryonated SPF eggs.
3. Class B SPF eggs are highly utilized for this purpose to ensure the resulting cell culture remains free of any vertically transmissible avian pathogens.
Step 4: Final Answer
The correct option is (C).
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