Question:

Which one of the following is NOT an antibiotic?

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Suffixes are helpful:
"-cycline" often indicates tetracyclines.
"-cillin" indicates penicillins.
"-sone" (like Betamethasone, Dexamethasone, Cortisone) usually indicates steroid hormones.
  • Tetracycline
  • Rifabutin
  • Amoxycillin
  • Betamethasone
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The Correct Option is D

Solution and Explanation

Step 1: Understanding the Question:
The question asks to identify the substance among the choices that does not function as an antibiotic. Antibiotics are antimicrobial substances used to treat bacterial infections.
Detailed Explanation:

Analyzing the Antibiotics:
Tetracycline: A broad-spectrum antibiotic that inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit.
Rifabutin: A bactericidal antibiotic used primarily to treat tuberculosis and infections related to MAC (Mycobacterium avium complex). It works by inhibiting DNA-dependent RNA polymerase.
Amoxycillin: A semi-synthetic, broad-spectrum antibiotic belonging to the penicillin family. It inhibits bacterial cell wall synthesis.

Betamethasone (The Correct Answer):
Betamethasone is a corticosteroid (steroid hormone).
It is used for its potent anti-inflammatory and immunosuppressive properties.
It is used to treat conditions like asthma, allergies, and skin diseases, but it has no direct antimicrobial or antibacterial activity.

Step 3: Final Answer:

Betamethasone is a steroid, not an antibiotic.
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