Question

Which one of the following antiplatelet agents is a reversible P2Y12 inhibitor?

• A. Clopidogrel
• B. Ticagrelor
• C. Ticlopidine
• D. Aspirin

Hint:

Ticagrelor is the only "reversible" one among the common ADP blockers.

Answer 1

The Correct Option is B

Step 1: Concept
Antiplatelet agents prevent blood clots by inhibiting platelet aggregation.

Step 2: Meaning
P2Y12 inhibitors block the ADP receptor on platelets. Most are thienopyridines that bind irreversibly.

Step 3: Analysis
Clopidogrel and Ticlopidine are irreversible inhibitors. Aspirin inhibits COX-1 irreversibly. Ticagrelor is a nucleoside analog that binds reversibly to the P2Y12 receptor.

Step 4: Conclusion
Ticagrelor is the correct example of a reversible P2Y12 inhibitor.

Final Answer: (B)