Question:
Which of the following sugars enters in the glycolysis via Leloir pathway?
Which of the following sugars enters in the glycolysis via Leloir pathway?
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Leloir pathway:
- Converts galactose to glucose-1-phosphate.
- Key enzymes: Galactokinase, Transferase, Epimerase.
- Galactose is a major sugar in milk (lactose).
- Converts galactose to glucose-1-phosphate.
- Key enzymes: Galactokinase, Transferase, Epimerase.
- Galactose is a major sugar in milk (lactose).
Updated On: Sep 1, 2026
- Fructose
- Mannose
- Galactose
- Deoxyribose
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The Correct Option is C
Solution and Explanation
Step 1: Understanding the Question:
This question tests knowledge of metabolic pathways for sugar catabolism.
Step 2: Detailed Explanation:
Galactose enters glycolysis via the Leloir pathway.
The pathway involves:
- Galactose kinase (converts galactose to galactose-1-phosphate).
- Galactose-1-phosphate uridylyltransferase (converts to UDP-galactose).
- UDP-galactose 4-epimerase (converts UDP-galactose to UDP-glucose).
- UDP-glucose is then converted to glucose-1-phosphate, which enters glycolysis.
Fructose (A): Enters glycolysis via the fructose-1-phosphate pathway.
Mannose (B): Enters glycolysis via conversion to fructose-6-phosphate.
Deoxyribose (D): Not a sugar that enters glycolysis.
Thus, galactose enters glycolysis via the Leloir pathway.
Step 3: Final Answer:
Thus, galactose enters glycolysis via the Leloir pathway, which corresponds to option (C).
[0.5cm]
This question tests knowledge of metabolic pathways for sugar catabolism.
Step 2: Detailed Explanation:
Galactose enters glycolysis via the Leloir pathway.
The pathway involves:
- Galactose kinase (converts galactose to galactose-1-phosphate).
- Galactose-1-phosphate uridylyltransferase (converts to UDP-galactose).
- UDP-galactose 4-epimerase (converts UDP-galactose to UDP-glucose).
- UDP-glucose is then converted to glucose-1-phosphate, which enters glycolysis.
Fructose (A): Enters glycolysis via the fructose-1-phosphate pathway.
Mannose (B): Enters glycolysis via conversion to fructose-6-phosphate.
Deoxyribose (D): Not a sugar that enters glycolysis.
Thus, galactose enters glycolysis via the Leloir pathway.
Step 3: Final Answer:
Thus, galactose enters glycolysis via the Leloir pathway, which corresponds to option (C).
[0.5cm]
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