Which of the following stages of cell division is primarily arrested by treating with colchicine, used in polyploidization of plants?
Show Hint
- Binds to tubulin (prevents spindle formation).
- Arrests metaphase.
- Causes chromosome duplication (polyploidy).
- Used in plant breeding for polyploidization.
- Anaphase
- Telophase
- Interphase
- Metaphase
The Correct Option is D
Solution and Explanation
This question tests knowledge of the mechanism of action of colchicine in polyploidization.
Step 2: Detailed Explanation:
Colchicine primarily arrests cell division at metaphase (D).
It binds to tubulin and prevents the formation of spindle fibers.
As a result, chromosomes cannot separate during anaphase.
The cell enters interphase without undergoing cytokinesis, resulting in chromosome duplication (polyploidy).
Other stages:
- Anaphase (A): Chromosomes separate; colchicine prevents this.
- Telophase (B): Final stage of mitosis.
- Interphase (C): Not affected by colchicine.
Thus, colchicine arrests metaphase to induce polyploidy.
Step 3: Final Answer:
Thus, colchicine primarily arrests metaphase, which corresponds to option (D).
[0.5cm]
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