Question:

Which of the following materials is used as an antigen in Casoni's test?

Show Hint

Immunodiagnostic Antigens:
Casoni's Test (Echinococcosis) $\rightarrow$ Sterile Hydatid Fluid.
Mallein Test (Glanders) $\rightarrow$ Culture filtrate of Burkholderia mallei.
Tuberculin Test $\rightarrow$ PPD.
  • Hydatid fluid
  • Adult worm
  • Egg
  • Protoscolices
Show Solution
collegedunia
Verified By Collegedunia

The Correct Option is A

Solution and Explanation


Step 1: Understanding the Concept:

Immediate hypersensitivity intradermal skin testing for immunological detection of hydatidosis (echinococcosis).

Step 2: Detailed Explanation:

Casoni's Test (Tomaso Casoni, 1912):
- An immediate Type I hypersensitivity intradermal skin test used for the immunodiagnosis of cystic echinococcosis (Hydatid Disease, Echinococcus granulosus).
- The diagnostic antigen used is sterile, Seitz-filtered Hydatid Fluid collected aseptically from fertile hydatid cysts of slaughtered sheep or cattle.
- Intradermal injection of $0.1 - 0.2\text{ mL}$ of hydatid fluid produces a diagnostic wheal-and-flare erythematous skin reaction within 15--20 minutes in sensitized individuals.

Step 3: Final Answer:

Hence, Hydatid fluid is used as the antigen in Casoni's test, matching option (A).
Was this answer helpful?
0
0