Step 1: Understanding the Concept:
Insecticide resistance develops due to the selection pressure of repeated chemical applications.
Managing resistance involves biochemical and operational strategies to suppress or bypass resistance mechanisms.
Step 2: Detailed Explanation:
One of the major mechanisms of physiological resistance is the metabolic detoxification of insecticides by enzymes like cytochrome P450 monooxygenases, esterases, or glutathione S-transferases (GSTs).
Synergists (such as Piperonyl Butoxide, PBO) are non-toxic chemicals that block these specific detoxification enzymes.
When co-applied with an insecticide, the synergist restores the susceptibility of resistant populations.
Other listed choices like using the same mode of action or doubling the dose will exacerbate and accelerate resistance development.
Step 3: Final Answer:
The correct option is (B).