Question:

Which of the following is the most abundant end product of fatty acid synthesis?

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Fatty acid synthase stops at 16 carbons - which saturated acid is that?
Updated On: Jun 24, 2026
  • Oleic acid
  • Palmitic acid
  • Arachidonic acid
  • Glucose
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The Correct Option is B

Solution and Explanation

Step 1: De-novo fatty acid synthesis occurs in the cytosol (extramitochondrial system) of liver, kidney, brain, lung, mammary gland, and adipose tissue, using acetyl-CoA as the immediate two-carbon building block.
Step 2: The fatty acid synthase complex elongates the chain two carbons at a time and stops at a 16-carbon saturated fatty acid, releasing palmitate (palmitic acid) as the principal product.
Step 3: Palmitate is therefore the most abundant end product; stearate forms in smaller amounts by further elongation. This makes (b) correct.
Step 4: Oleic acid (c18:1) and arachidonic acid (c20:4) require additional desaturation and elongation downstream and are not the direct synthase product; glucose is not a fatty acid at all, so (a), (c), and (d) are wrong.
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