Question:

Which of the following is NOT present in the inner mitochondrial membrane?

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Membrane Locations: Inner Mitochondrial Membrane = Complexes I, II, III, IV, and V (ATP Synthase). Glycophorin = RBC Plasma Membrane.
  • NADH-Q reductase
  • ATP synthase
  • Q-cytochrome c reductase
  • Glycophorine
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The Correct Option is D

Solution and Explanation


Step 1: Understanding the Concept:

The inner mitochondrial membrane contains respiratory chain complexes and ATP synthase, while glycophorin is an erythrocyte plasma membrane protein.

Step 2: Detailed Explanation:

Evaluating the membrane proteins:
1. NADH-Q Reductase (Complex I): Integral inner mitochondrial membrane complex.
2. Q-Cytochrome c Reductase (Complex III): Integral inner mitochondrial membrane complex.
3. ATP Synthase (Complex V): Inner mitochondrial membrane rotary catalyst.
4. Glycophorin (Glycophorin A): A heavily sialylated, single-pass transmembrane glycoprotein found exclusively in the plasma membrane of red blood cells (erythrocytes), functioning to prevent RBC aggregation.

Step 3: Final Answer:

Thus, Glycophorin is NOT present in the inner mitochondrial membrane, matching option (D).
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