Question:

Which of the following is NOT a ketone body?

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Ketone bodies:
- Acetone, Acetoacetate, \(\beta\)-hydroxybutyrate.
- Produced during fasting, diabetes, and low-carbohydrate diets.
  • Acetone
  • Acetoacetate
  • \(\beta\)-hydroxybutyrate
  • Isobutyryl CoA
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The Correct Option is D

Solution and Explanation

Step 1: Understanding the Question:
This question tests knowledge of ketone bodies and metabolism.

Step 2: Detailed Explanation:

The three ketone bodies are:
1. Acetone
2. Acetoacetate
3. \(\beta\)-hydroxybutyrate
They are produced during ketogenesis when acetyl-CoA accumulates.
Isobutyryl CoA (D) is an intermediate in amino acid metabolism (valine degradation).
It is not a ketone body.
Thus, isobutyryl CoA is not a ketone body.

Step 3: Final Answer:

Thus, isobutyryl CoA is NOT a ketone body, which corresponds to option (D).
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