Question:

Which of the following is an example of an amide-type local anesthetic?

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Local anesthetics are split into two families based on the linking group in the middle of the molecule: ester-type and amide-type.
Updated On: Jun 24, 2026
  • Procaine
  • Lidocaine
  • Benzocaine
  • Tetracaine
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The Correct Option is B

Solution and Explanation

Concept:
Local anesthetics are split into two families based on the linking group in the middle of the molecule: ester-type and amide-type. A simple memory trick is that amide-type drugs usually have two letter "i"s in their name.

Step 1:
Procaine, Benzocaine and Tetracaine all contain an ester linkage, so they are ester-type local anesthetics.

Step 2:
Lidocaine contains an amide linkage in its structure, which makes it the amide-type local anesthetic. (Notice it has two "i"s: L-i-doca-i-ne.)

Answer: Option (2) — Lidocaine.
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