Question:

Which of the following hematology changes is seen in acute diffuse peritonitis with toxemia?

Show Hint

An overwhelming, acute purulent inflammation (like peritonitis, metritis, or mastitis) in ruminants and horses typically results in a degenerative left shift.
The tissue demand simply exhausts the bone marrow's storage capacity.
  • Regenerative left shift
  • Degenerative left shift
  • Regenerative right shift
  • Degenerative right shift
Show Solution
collegedunia
Verified By Collegedunia

The Correct Option is B

Solution and Explanation

Step 1: Understanding the Concept:
In veterinary hematology, a "left shift" indicates the presence of immature neutrophils (band cells) in circulation.
- Regenerative left shift: Neutrophilia with immature forms, indicating that the bone marrow is successfully keeping up with tissue demand.
- Degenerative left shift: Immature neutrophils outnumber mature neutrophils, often accompanied by leukopenia.
This indicates that tissue consumption of neutrophils is faster than the bone marrow's rate of production and release.

Step 2: Detailed Explanation:

Let us examine the pathogenesis of acute diffuse peritonitis with toxemia:
- Diffuse peritonitis represents a massive, acute inflammatory process in the peritoneal cavity.
- Immature and mature neutrophils are rapidly sequestered from circulation into the abdominal cavity to fight infection.
- This rapid consumption depletes the mature pool in the blood.
- The bone marrow releases its storage pool of immature (band) neutrophils to compensate, but cannot keep up with the overwhelming demand.
- Toxemia further suppresses bone marrow function, resulting in a classic degenerative left shift (leukopenia with a high proportion of band neutrophils).

Step 3: Final Answer:

Thus, the correct hematological change seen in this condition is a degenerative left shift.
Was this answer helpful?
0
0

Top ICAR AIEEA Radiology Questions

View More Questions