Which of the following formulations are “pharma- ceutically equivalent"? Match the List-I with List-II Ingrediant Function Table A Table B Table C Table D A Aceta- minophen I Drug 300 mg - 300 mg 300 mg B Aspirin II Drug - 300 mg - - C Lactose III Filler 100 mg 100 mg - 100 mg D Avicel IV Filler - - 100 mg - starch Dis-integrant 50 mg 50 mg - 50 mg Avicel Dis-integrant - - 50 mg - Magsterate Lubricant 2 mg 2 mg 2 mg 2 mg Gelatin Binder 10 mg 10 mg 10 mg 10 mg Choose the correct answer from the options given below:

Question

Which of the following formulations are “pharma- ceutically equivalent"? Match the List-I with List-II Ingrediant   Function Table A Table B Table C Table D A Aceta- minophen I Drug 300 mg - 300 mg 300 mg B Aspirin II Drug - 300 mg - - C Lactose III Filler 100 mg 100 mg  - 100 mg D Avicel IV Filler - - 100 mg -   starch   Dis-integrant 50 mg 50 mg - 50 mg   Avicel   Dis-integrant - - 50 mg -   Magsterate   Lubricant 2 mg 2 mg 2 mg 2 mg   Gelatin   Binder 10 mg 10 mg 10 mg 10 mg Choose the correct answer from the options given below:

Collegedunia Admin · Accepted Answer

The correct option is (C): A and C

Answer

Answer

Answer

Answer

List I		List II
A	Grignard reagent	I	R₂CuLi
B	Gilman reagent	II	RMgX
C	Benzyne mechanism	III	2 molecules of CH₃CHO
D	Aldol condensation	IV	S_NAr

List I (Antiretrovirus Drugs)		List II (Mechanism of Action)
A.	Lamivudine	I.	Integrase inhibitors
B.	Efavirenz	II.	Protease inhibitors
C.	Ritonavir	III.	Nucleoside reverse transcriptase inhibitors
D.	Raltegravir	IV.	Non-nucleoside reverse transcriptase inhibitors.

List I (Antimicrobial Agent)		List II (Systemic toxicity)
A.	Aminoglycosides	I.	Hearing loss, kidney damage
B.	Tetracyclines	II.	Neurological and renal toxicity
C.	Vancomycin	III.	8th cranial nerve and kidney toxicity
D.	Polymyxin B	IV.	Liver and kidney damage, anti anabolic effect

The Correct Option is C

Solution and Explanation

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	Ingrediant		Function	Table A	Table B	Table C	Table D
A	Aceta- minophen	I	Drug	300 mg	-	300 mg	300 mg
B	Aspirin	II	Drug	-	300 mg	-	-
C	Lactose	III	Filler	100 mg	100 mg	-	100 mg
D	Avicel	IV	Filler	-	-	100 mg	-
	starch		Dis-integrant	50 mg	50 mg	-	50 mg
	Avicel		Dis-integrant	-	-	50 mg	-
	Magsterate		Lubricant	2 mg	2 mg	2 mg	2 mg
	Gelatin		Binder	10 mg	10 mg	10 mg	10 mg