Step 1: Understanding the Concept:
Enzymes have specific properties.
These properties determine their function.
Step 2: Key Formula or Approach:
No specific formula.
Need to understand enzyme properties.
Step 3: Detailed Explanation:
A. Enzymes cannot change the equilibrium constant - correct.
B. Active site properties limit substrate specificity - correct.
C. Enzymes may require cofactors (metals, organic coenzymes) - correct.
D. pH affects enzyme activity - incorrect.
Thus, A, B, and C are correct.
Step 4: Final Answer:
The correct statements are A, B, and C.
Hence, the correct option is (B).