Question:

Which of the following are NOT chain initiation codons
A. UAA
B. UAG
C. UGA
D. AUG
E. GUG
Choose the correct answer from the options given below:

Show Hint

Remember the stop codons with a phrase: U Are Away, U Are Gone, U Go Away.
  • A, B and D only
  • B, C and E only
  • A, B and C only
  • D and E only
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The Correct Option is C

Solution and Explanation

Step 1: Understanding the Question:
The question involves understanding the genetic code, specifically identifying which three-letter sequences (codons) on mRNA do not signal the start of protein synthesis (translation).
Detailed Explanation:

Initiation Codons: These are the codons that signal the ribosome to start translating a protein.
- AUG (D): The universal start codon. It codes for the amino acid methionine.
- GUG (E): An alternative start codon in some prokaryotes, though it normally codes for valine.

Termination Codons (Stop Codons): These are codons that do not signal initiation but instead signal the end of protein synthesis. They do not code for any amino acid. The three stop codons are:
- UAA (A): Known as Ochre.
- UAG (B): Known as Amber.
- UGA (C): Known as Opal.

Conclusion: Since A, B, and C are stop codons, they are not initiation codons.
Final Answer:
The codons UAA, UAG, and UGA are termination codons. Thus, option (C) is the correct answer.
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