Question:

Which drug is not included among DMARDs?

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One of these is a vinca alkaloid anticancer drug, not an antirheumatic agent.
Updated On: Jun 24, 2026
  • Chloroquine
  • Vincristine
  • Azathioprine
  • Leflunomide
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The Correct Option is B

Solution and Explanation

Step 1: DMARDs (disease modifying antirheumatic drugs) slow the progression of rheumatoid arthritis rather than just relieving pain. They include methotrexate, sulfasalazine, chloroquine or hydroxychloroquine, leflunomide, azathioprine, cyclosporine, gold salts and d-penicillamine, plus biologics.

Step 2: Chloroquine, azathioprine and leflunomide are all recognised DMARDs, so they are not the answer.

Step 3: Vincristine is a vinca alkaloid anticancer agent that inhibits microtubule assembly. It is used in leukaemias and lymphomas, not as a DMARD.

Step 4: Therefore vincristine is the drug that does not belong, making it the correct choice.
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