Question:
Which drug does NOT belong to the glycosides group?
Which drug does NOT belong to the glycosides group?
Show Hint
The three standard cardiotonic glycosides used in clinical veterinary medicine are Digoxin, Digitoxin, and Ouabain.
Glycyrrhizin is a licorice-derived saponin and lacks cardiotonic activity.
Glycyrrhizin is a licorice-derived saponin and lacks cardiotonic activity.
Updated On: Aug 24, 2026
- Digitoxin
- Digoxin
- Ouabain
- Glycyrrhizin
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The Correct Option is D
Solution and Explanation
Step 1: Understanding the Concept:
Glycosides are organic compounds composed of a sugar portion (glycone) and a non-sugar portion (aglycone) bound together by a glycosidic bond.
In pharmacology, cardiac glycosides are a specific therapeutic class of glycosides used to treat congestive heart failure.
Step 2: Detailed Explanation:
Let us analyze the classification of each drug:
- Digitoxin: A cardiotonic steroid glycoside obtained from the foxglove plant, *Digitalis purpurea*.
- Digoxin: A widely used cardiac glycoside isolated from *Digitalis lanata*.
- Ouabain: A highly potent, fast-acting cardiac glycoside obtained from the seeds of *Strophanthus gratus*.
- Glycyrrhizin: The principal sweet-tasting compound of licorice root (*Glycyrrhiza glabra*).
While chemically a triterpenoid saponin glycoside, in clinical veterinary pharmacology, it is not grouped under the standard therapeutic glycosides (cardiac glycosides) used for cardiovascular therapy.
Step 3: Final Answer:
Therefore, Glycyrrhizin is the drug that does not belong to the primary therapeutic cardiac glycoside group.
Glycosides are organic compounds composed of a sugar portion (glycone) and a non-sugar portion (aglycone) bound together by a glycosidic bond.
In pharmacology, cardiac glycosides are a specific therapeutic class of glycosides used to treat congestive heart failure.
Step 2: Detailed Explanation:
Let us analyze the classification of each drug:
- Digitoxin: A cardiotonic steroid glycoside obtained from the foxglove plant, *Digitalis purpurea*.
- Digoxin: A widely used cardiac glycoside isolated from *Digitalis lanata*.
- Ouabain: A highly potent, fast-acting cardiac glycoside obtained from the seeds of *Strophanthus gratus*.
- Glycyrrhizin: The principal sweet-tasting compound of licorice root (*Glycyrrhiza glabra*).
While chemically a triterpenoid saponin glycoside, in clinical veterinary pharmacology, it is not grouped under the standard therapeutic glycosides (cardiac glycosides) used for cardiovascular therapy.
Step 3: Final Answer:
Therefore, Glycyrrhizin is the drug that does not belong to the primary therapeutic cardiac glycoside group.
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