Question:
Which derivatives of the following produce good antianginal drugs?
Which derivatives of the following produce good antianginal drugs?
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Antianginal drugs relieve chest pain caused by the heart not getting enough blood. One important group of these drugs is the calcium channel blockers.
Updated On: Jun 24, 2026
- 1,2 Dihydro Pyridine
- 1,3 Dihydro Pyridine
- 1,4 Dihydro Pyridine
- Pyridine
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The Correct Option is C
Solution and Explanation
Concept:
Antianginal drugs relieve chest pain caused by the heart not getting enough blood. One important group of these drugs is the calcium channel blockers.
Step 1:
Many well-known calcium channel blockers, such as nifedipine and amlodipine, are built on a 1,4-dihydropyridine ring. This ring is the key part that gives them their heart and blood-vessel action.
Step 2:
The other ring patterns (1,2- and 1,3-dihydropyridine) and plain pyridine do not give this useful antianginal activity, so they are not the answer.
Answer: Option (3) — 1,4 Dihydro Pyridine.
Antianginal drugs relieve chest pain caused by the heart not getting enough blood. One important group of these drugs is the calcium channel blockers.
Step 1:
Many well-known calcium channel blockers, such as nifedipine and amlodipine, are built on a 1,4-dihydropyridine ring. This ring is the key part that gives them their heart and blood-vessel action.
Step 2:
The other ring patterns (1,2- and 1,3-dihydropyridine) and plain pyridine do not give this useful antianginal activity, so they are not the answer.
Answer: Option (3) — 1,4 Dihydro Pyridine.
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