Step 1: Define buboes. A bubo is an inflamed, swollen lymph node, particularly in the inguinal or axillary region. An outbreak of buboes in a community is the classic presentation of
bubonic plague, caused by
Yersinia pestis.
Step 2: Identify the transmission cycle. Plague is a zoonotic disease. Rats are the primary reservoir. The vector that transmits
Yersinia pestis from infected rats to humans is the
Xenopsylla cheopis (Oriental rat flea). When a rat dies, its fleas seek a new host and may bite humans, regurgitating the bacteria during the blood meal.
Step 3: Eliminate wrong options.- Tsetse fly -- transmits Trypanosoma brucei (sleeping sickness)
- Human flea (Pulex irritans) -- can transmit plague in rare circumstances but is NOT the primary vector
- Sand fly -- transmits Leishmania species
Step 4: Epidemiological significance. When infected rat fleas bite humans,
Yersinia pestis enters the lymphatics, causing massive lymph node enlargement (bubo). If untreated, bacteraemia and septicaemia follow, with >50% mortality.
Step 5: Conclusion. Xenopsylla cheopis (rat flea) is the primary vector of bubonic plague.