Question:
Theiler's disease is the most common cause of acute hepatitis in
Theiler's disease is the most common cause of acute hepatitis in
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Theiler's Disease: Acute Serum Hepatitis in HORSES caused by Equine Parvovirus-Hepatitis (EqPV-H) following biological product administration.
Updated On: Sep 7, 2026
- Cattle
- Sheep and Goat
- Dogs
- Horse
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The Correct Option is D
Solution and Explanation
Step 1: Understanding the Concept:
Equine serum hepatitis (Theiler's disease) is a fulminant viral hepatopathy associated with biological equine serum administration.
Step 2: Detailed Explanation:
Theiler's Disease (Equine Serum Hepatitis Acute Hepatic Necrosis of Horses):
- First described by Sir Arnold Theiler in 1919 in horses receiving equine-origin antiserum (tetanus antitoxin).
- It is the most common cause of acute fulminant liver failure and hepatic encephalopathy in the Horse.
- It is caused by Equine Parvovirus-Hepatitis (EqPV-H) and Equine Pegivirus transmitted via biologic blood/serum products or natural exposure, leading to diffuse centrilobular to massive hepatic necrosis ('dishrag liver').
Step 3: Final Answer:
Therefore, Theiler's disease is the most common cause of acute hepatitis in Horses, matching option (D).
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