Question:

The mammalian neurohypophysis is the source of which of the following principal hormone(s)?
A. Oxytocin
B. Arginine vasopressin
C. Lysine vasopressin
D. Corticosteroid
Choose the correct answer from the options given below

Show Hint

Neurohypophyseal Hormones: Oxytocin + Arginine Vasopressin (AVP ADH). (Swine have Lysine Vasopressin; Adrenal Cortex secretes Corticosteroids).
  • A only
  • A and B only
  • A, B and C only
  • All A, B, C and D
Show Solution
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The Correct Option is B

Solution and Explanation


Step 1: Understanding the Concept:

Neurohypophyseal nonapeptides: the posterior pituitary (neurohypophysis) stores and releases oxytocin and arginine vasopressin synthesized in hypothalamic magnocellular nuclei.

Step 2: Detailed Explanation:

Endocrinology of the posterior pituitary (neurohypophysis):
1. A. Oxytocin: Nonapeptide synthesized in paraventricular/supraoptic nuclei, released from neurohypophyseal axonal terminals for milk ejection and myometrial contractions.
2. B. Arginine Vasopressin (AVP Antidiuretic Hormone ADH): The universal mammalian antidiuretic hormone (present in all domestic mammals except swine).
3. C. Lysine Vasopressin (LVP): A species-specific vasopressin variant found only in swine (Suidae) and hippopotamuses, not the general mammalian standard.
4. D. Corticosteroids: Synthesized by the adrenal cortex.
Therefore, the principal mammalian neurohypophyseal hormones are A and B only.

Step 3: Final Answer:

Thus, the principal hormones are A and B only, matching option (B).
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