Question:
The drug of choice for resistant rheumatic chorea is:
The drug of choice for resistant rheumatic chorea is:
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An anticonvulsant that boosts GABA is the preferred symptomatic agent.
Updated On: Jun 24, 2026
- Valproate
- Haloperidol
- Diazepam
- Probenecid
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The Correct Option is A
Solution and Explanation
Step 1: Rheumatic chorea (Sydenham chorea) follows an abnormal immune response to group A streptococcal infection and produces rapid, uncoordinated jerking movements of the face, hands and feet.
Step 2: The chorea responds poorly to antirheumatic drugs, so symptomatic treatment is used. Anticonvulsants such as valproate and carbamazepine, plus neuroleptics such as haloperidol and pimozide, are the mainstays.
Step 3: Among the options, valproate is the preferred drug of choice for resistant rheumatic chorea. Probenecid is a uricosuric for gout and has no role, making valproate correct.
Step 2: The chorea responds poorly to antirheumatic drugs, so symptomatic treatment is used. Anticonvulsants such as valproate and carbamazepine, plus neuroleptics such as haloperidol and pimozide, are the mainstays.
Step 3: Among the options, valproate is the preferred drug of choice for resistant rheumatic chorea. Probenecid is a uricosuric for gout and has no role, making valproate correct.
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