Step 1: Write the required integral.
The area under the curve is
\[
\int_1^2 x^5e^{x^3}\,dx
\]
Step 2: Use substitution.
Let
\[
u=x^3
\]
Then,
\[
\frac{du}{dx}=3x^2
\]
\[
du=3x^2dx
\]
So,
\[
x^2dx=\frac{du}{3}
\]
Now rewrite the integral:
\[
x^5dx=x^3(x^2dx)
\]
Since
\[
x^3=u,
\]
we get
\[
x^5dx=u\frac{du}{3}
\]
Step 3: Change the limits.
When
\[
x=1,\quad u=1^3=1
\]
When
\[
x=2,\quad u=2^3=8
\]
Thus, the integral becomes
\[
\int_1^8 \frac{u}{3}e^u\,du
\]
\[
=\frac{1}{3}\int_1^8 ue^u\,du
\]
Step 4: Integrate by parts.
We know that
\[
\int ue^u\,du=e^u(u-1)
\]
Therefore,
\[
\frac{1}{3}\left[e^u(u-1)\right]_1^8
\]
Step 5: Substitute the limits.
\[
=\frac{1}{3}\left[e^8(8-1)-e^1(1-1)\right]
\]
\[
=\frac{1}{3}\left[7e^8-0\right]
\]
\[
=\frac{7}{3}e^8
\]
Step 6: Final conclusion.
Hence, the area under the curve is
\[
\boxed{\frac{7}{3}e^8}
\]
Therefore, the correct option is (D).