Question:
The antinutritional compound that interferes with the uptake of iodine by thyroid glands is
The antinutritional compound that interferes with the uptake of iodine by thyroid glands is
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Brassica vegetables (cabbage, cauliflower, mustard greens) contain glucosinolates, which release goitrogenic compounds upon tissue disruption.
Updated On: Sep 15, 2026
- Saponins
- Tannin
- Goitrogens
- Hemagglutinins
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The Correct Option is C
Solution and Explanation
Step 1: Understanding the Concept:
Antinutritional factors interfere with the bio-accessibility, absorption, and metabolic uptake of essential micronutrients.
Step 2: Detailed Explanation:
Goitrogens (such as thiocyanates, isothiocyanates, and goitrins formed from glucosinolates) competitively inhibit the sodium-iodide symporter in thyroid follicular cells.
This prevents iodine uptake, impeding the synthesis of triiodothyronine ($T_3$) and thyroxine ($T_4$), which stimulates thyroid-stimulating hormone (TSH) and causes goiter.
Step 3: Final Answer:
Thus, goitrogens are the antinutritional compounds that interfere with thyroid iodine uptake.
Antinutritional factors interfere with the bio-accessibility, absorption, and metabolic uptake of essential micronutrients.
Step 2: Detailed Explanation:
Goitrogens (such as thiocyanates, isothiocyanates, and goitrins formed from glucosinolates) competitively inhibit the sodium-iodide symporter in thyroid follicular cells.
This prevents iodine uptake, impeding the synthesis of triiodothyronine ($T_3$) and thyroxine ($T_4$), which stimulates thyroid-stimulating hormone (TSH) and causes goiter.
Step 3: Final Answer:
Thus, goitrogens are the antinutritional compounds that interfere with thyroid iodine uptake.
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